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GEN
1 天
Targeting “Proteolethargy” to Restore Protein Mobility May Represent Therapeutic ...
Researchers hope findings will lead to new class of drugs for many different diseases for which proteolethargy is a common ...
GEN
1 天
Rare Genetic Disorder Helps Explain Link Between Cancer Immunotherapy and Increased Infections
Studying patients with PD-1 or PD-L1 deficiency may help inform new approaches to fine-tuning immunotherapies to maximise ...
GEN
2 天
The Locus Coeruleus Acts as a Gatekeeper of Sleep Stages
The locus coeruleus was found to facilitate the transition between NREM and REM sleep states while maintaining an unconscious ...
GEN
2 天
Triggering Necroptosis in Tumor Cells Can Backfire in a Cloud of IL-1a
Cancer cell death via necroptosis can be accompanied by the release of IL-1a, which can restrict anticancer immunity and ...
GEN
3 天
Bridgebio’s Attruby, to Treat Heart Condition ATTR-CM, Receives FDA Approval
Attruby (acoramidis), a near complete TTR stabilizer, has been approved by FDA to reduce cardiovascular death and ...
GEN
3 天
Bitter Taste Receptor Engages Compounds Not Just Outside the Cell, but Inside
Bitter taste receptor has hidden intracellular pocket that enables activation via simultaneous extracellular/intracellular ...
GEN
3 天
Novel Mechanism Unraveled in DNA Gyrase, Opening Pathways for Antibiotic Therapeutics
Using high-resolution cryo-electron microscopy researchers uncovered unprecedented detail of gyrase’s action on DNA.
GEN
4 天
StockWatch: Moderna Seeks to Reassure Investors on RFK Jr.
Moderna’s top executives have sought to reassure investors they will be able to carry out the comeback plans announced in ...
GEN
4 天
Trump to Nominate Makary for FDA Commissioner
Martin A. Makary, MD, of Johns Hopkins University, a critic of vaccination schedules and COVID-19 measures promulgated by ...
GEN
8 天
Human Antibody Discovery May Point to Vaccines Protecting Against Severe Malaria
Researchers suggest broadly reactive antibodies identified are likely to represent a common mechanism of acquired immunity to ...
GEN
6 天
Repair Proteins Collaborate in “Hubs” to Repair DNA Damage
Researchers have mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...
GEN
6 天
snoRNA Target Discoveries Could Lead to Potential Therapeutic Strategies
A new approach for identifying new cellular RNA targets of snoRNAs uncovered thousands of previously unknown targets ...
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