Espin induces abundant filopodia formation at the leading edge and along the sides, exerting force for cells migrating in ...

Inflammatory arthritis encompasses a group of autoimmune diseases, including rheumatoid arthritis (RA), psoriatic arthritis ...

Using genetically predicted metabolic reaction fluxes, the authors identify reactions that can amplify or buffer the effect ...

This collection highlights recent ‘Proteomics’ content published in Molecular Systems Biology. The featured Reviews and Research Articles showcase the value of proteomics data as resources for the ...

GAS2 is a cytoskeletal regulator that interacts with both F-actin and microtubules. Here, cryo-EM structures of GAS2 domains ...

The last few years have provided us with a new level of understanding of how chromosomes are replicated, segregated and read - and how their 3D organisation influences expression of individual genes ...

Brian's research focuses intersections between circadian rhythm and cancer. He utilizes cell line and mouse models of MYC-driven lung cancer to focus on how amplified MYC and metabolic stress disrupt ...

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The EMBO Journal publishes papers describing original research of broad general interest in molecular and cell biology - a particular emphasis is placed on molecular ...

Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...

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