Background In patients who have been mechanically ventilated, inspiratory muscles remain weak and fatigable following ventilatory weaning, which may contribute to dyspnoea and limited functional ...

Guidelines on contraindications for lung function tests have been based on expert opinion from >30 years ago. High-risk contraindications to lung function testing are associated with cardiovascular ...

Background Conflicting evidence has emerged regarding the relevance of smoking on risk of COVID-19 and its severity. Methods We undertook large-scale observational and Mendelian randomisation (MR) ...

Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, UK Dr Sophie D West, Sleep Unit, Oxford Centre for Respiratory Medicine, Churchill Hospital, Old Road, Oxford OX3 ...

a Royal Brompton Hospital and Imperial College School of Medicine at the National Heart & Lung Institute, London SW3 6NP, UK, b MRC Immunochemistry Unit, Department of Biochemistry, University of ...

Background Decline in forced vital capacity (FVC) over time reliably predicts mortality in patients with idiopathic pulmonary fibrosis. The use of this measure in clinical practice is recommended by ...

a Department of Respiratory Medicine, Sleep Laboratory and PRETA Laboratory, CHRU, Grenoble, France, b Respiratory Department, Bristol Royal Infirmary, Bristol, UK Professor PA Levy, EFCR, Pneumologie ...

2 (Co-Chair), The Queen’s University of Belfast, Belfast, UK 3 (Co-Chair), University Hospitals of Leicester, Glenfield Hospital, Leicester, UK Correspondence to: Professor A H Morice University of ...

Inflammation in preschool cystic fibrosis is of mixed phenotype, extends beyond the lung and is differentially modified by CFTR modulators ...

Background The bronchial epithelium and underlying reticular basement membrane (RBM) have a close spatial and functional inter-relationship and are considered an epithelial–mesenchymal trophic unit ...

Department of Pediatrics, Montréal Children’s Hospital, McGill University, Montréal, Québec, Canada Correspondence to: Dr R T Brouillette Department of Pediatrics, Montréal Children’s Hospital, 2300 ...

1 Institute of Occupational and Environmental Medicine, School of Population and Health Sciences, University of Birmingham, Birmingham, UK 2 Division of Applied Health Sciences, University of Aberdeen ...