Clinic for Internal Medicine I, University Hospital of Ulm, Ulm, Germany Background: CD147 (basigin, EMMPRIN) is a multifunctional, highly conserved glycoprotein enriched in pancreatic ductal ...

Using a double-lumen tube perfusion system, solutions of glucose (1·0, 2·5, and 5·0 g 100ml −1) have been perfused into the upper jejunum of 22 Zambian African subjects in order to study their glucose ...

Systemic messenger RNA replacement therapy is effective in a novel clinically relevant model of acute intermittent porphyria developed in non-human primates ...

Dr C Feinle, Gastroenterology Division, University Hospital Zurich, Rämistr. 100, 8091 Zurich, Switzerland. BACKGROUND/AIMS We aimed to evaluate the role of fat and cholecystokinin (CCK) in the ...

Inflammatory bowel disease and Parkinson’s disease are chronic progressive disorders that mainly affect different organs: the gut and brain, respectively. Accumulating evidence has suggested a ...

2 Laboratory of Molecular Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University School of Oncology, Beijing Cancer Hospital/Institute, ...

1 Department of Medical Genetics and Department of Pathology, Haartman Institute, PO Box 63, FIN-00014 University of Helsinki, Finland 2 Department of Medical Genetics, Haartman Institute, PO Box 63, ...

Objective We explored the hypothesis that TGR5, the bile acid (BA) G-protein-coupled receptor highly expressed in biliary epithelial cells, protects the liver against BA overload through the ...

Correspondence to Marc G Besselink, Department of Surgery, Amsterdam Gastroenterology and Metabolism, AMC Amsterdam, 22660, Amsterdam, The Netherlands; m.g.besselink{at}amc.uva.nl Acute pancreatitis ...

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Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic liver disease globally and is currently estimated to affect up to 38% of the global adult population. NAFLD is a ...

Correspondence to Dr Ka Shing Cheung, Department of Medicine, The University of Hong Kong, Hong Kong 999077, Hong Kong; cks634{at}hku.hk; Prof Wai-Kay Seto; wkseto{at}hku.hk Objective Whether varying ...