If you have treatment-resistant depression, you've already tried taking antidepressants without much success. But you shouldn't give up. It can take time to find the medication, dose, or mix of ...

If your depression doesn’t respond to treatment at first, you have other options. Learn more about therapies for treatment-resistant depression.

Introduction Major depressive disorder (MDD) is a major global healthcare challenge. This is, in part, due to the lack of treatment response and chronic course of MDD. Such a course of illness is ...

Electroconvulsive therapy was arguably the first treatment for serious depression to be developed. The Hungarian psychiatrist, Joseph Ladislav von Meduna published a report in 1935 that ...

Deep transcranial magnetic stimulation was safe and effective in treating adolescents and young adults with major depressive ...

Brief Treatment Strategies for Major Depressive Disorder: ... Hopko, SD. A brief behavioral activation treatment for depression: treatment manual. Behav Mod. 2001;25:255-286.

Augmentation was more effective with quetiapine than lithium for treatment-resistant depression in a pragmatic trial. Quetiapine also improved quality-adjusted life years more than lithium. The ...

Earlier identification is also of interest due to the possibility that earlier intervention may be more effective with more ...

For decades, researchers have been trying to devise safe and effective treatments for depression that cause minimal or no side effects. This led to the introduction of a wide range of treatment ...

Antidepressants, the gold standard treatment for depression, don’t work for many people. Will psilocybin be an alternative?

Three versions of synthetic psilocybin have received the US Food and Drug Administration’s “breakthrough therapy” designation — in 2018 for treatment-resistant depression, which is ...