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Lipid transporters E-Syt3 and ORP5 regulate epithelial ion transport by controlling phosphatidylserine enrichment at ER/PM junctions ...
Furthermore, we identified the polybasic motif in the C2B domain that facilitates SV release. Finally, we found that disruption of C1 and C2B membrane interaction in UNC-13S, the short isoform, leads ...
Recruitment of NLRP3 to the Golgi is controlled by the reversible addition of a lipid anchor adjacent to the polybasic region.
The wide distribution of the polybasic domain, but not an α0 helix in which it is found in opisthokonts, suggests that the role of ancestral septins involved their binding to lipid bilayers.
Researchers evaluated the importance of the P681 residue within the furin cleavage site of SARS-CoV-2 spike protein in determining the fusogenicity and syncytia formation ability of SARS-CoV-2 ...
Electrostatics have been thought to dominate interactions between a polybasic membrane anchoring motif and anionic lipids in the plasma membrane. Combining data from computational and imaging ...
Electrostatics have been thought to dominate interactions between a polybasic membrane anchoring motif and anionic lipids in the plasma membrane. Combining data from computational and imaging ...