Researchers have found that the timing of when fluoxetine (commonly known by its brand name, Prozac) is administered is vital in determining the ...

Introduction Major depressive disorder (MDD) is a major global healthcare challenge. This is, in part, due to the lack of treatment response and chronic course of MDD. Such a course of illness is ...

Deep transcranial magnetic stimulation was safe and effective in treating adolescents and young adults with major depressive ...

Hu, J.S., Chen, Q.Y. and Yu, T.X. (2025) Emotion Regulation and Depression Symptoms among Chinese Adolescents: The Sequential Mediation Effect of Social Anxiety and Loneliness. Open Journal of Social ...

Saffron shows promise as a natural treatment for depression and cognitive decline, performing as well as standard drugs in ...

More information: Krutika Nagpurkar et al, Neurosteroids as emerging therapeutics for treatment-resistant depression: Mechanisms and clinical potential, Neuroscience (2025).

About 13 percent of Americans have postpartum depression (PPD), a condition that occurs within the first year after childbirth. It’s one of the most common health issues pregnant people ...

The term "treatment-resistant depression" is not frequently used in clinical settings. Terms such as "difficult-to-treat," "struggling with their condition," "complex needs," or "chronic" may be used ...

Background The comparative effectiveness of non-pharmacological treatments of depression remains unclear. Methods We conducted an overview of systematic reviews to identify randomised controlled ...

Creatine – best known for its use by bodybuilders – could help enhance the effects of talking therapy as a treatment for depression, recent research suggests. Around 280 million people have ...

The study, which used the Hamilton Depression Rating Scale (HDRS), revealed that TMS produced an average clinically meaningful decrease on of more than four points compared with the sham treatment.