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Top-down proteomics: Intact proteins are ionized and analyzed directly, allowing for the study of proteoforms and ...

The role of centrosomal tubulin glutamylation has remained elusive for decades. Here, a new tool enables precise ...

Each journal is staffed by professional editors who work in collaboration with one another and our international Editorial Advisory Boards of leading scientists. Please feel free to contact any of the ...

How chromatin openness controls behavioral changes remains unclear. This work implicates alternative promoter selection, ...

Several transcription factors in developing neurons exhibit broad-to-restricted expression patterns, but the relevance of ...

Cysts, fibrosis, and tubular degeneration form the typical triad of pathologies leading to the gradual decline in kidney ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. By combining the analysis of active enhancer ...

Mitochondrial diseases, arising from mutations in mitochondrial DNA (mtDNA), are a diverse group of disorders that lead to ...

Malaria parasites undergo an extensive metamorphosis after invasion of erythrocytes. This induces an increase in the surface area of the parasite, a change to an amoeboid shape and requires the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Immune memory plays a critical role in the ...