Facundo D. Batista (Chief Editor) Facundo is the Phillip T. and Susan M. Ragon Professor of Microbiology and Immunology at Harvard Medical School, and Associate Director of the Ragon Institute of MGH, ...

Spatial metabolomics is transforming our understanding of microbial systems by uncovering the localized molecular dynamics ...

EMBO Press publishes five scientific journals: The EMBO Journal - Submit here The EMBO Journal has been EMBO's flagship publication for 40 years. With a scope that spans all areas of molecular biology ...

A previous study showed that the predominant macrophage population during the mid-stage of skin wound healing (3–5 days post-injury) expresses CD206 and can be further divided into CD301b-positive and ...

A complex regulatory network is known to promote functional exhaustion of CD8 + T-cells, but less is known about those factors that protect CD8 + T-cells from exhaustion. This study identifies the ...

In this study, we demonstrated that the druggable NCoR1/RARα axis is a promising target for selective inhibition of CMA in NSCLC. Furthermore, we developed CIM7, a first-in-class small molecule ...

Abstract The mitochondrial F 1 F 0 -ATP synthase is crucial for maintaining the ATP/ADP balance which is critical for cell metabolism, ion homeostasis and cell proliferation. This enzyme, conserved ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Synthetic biology approaches such as ...

Results In this study, we show how hyperoxia at birth increases the number of alveolar type 1 (AT1) epithelial cells expressing the proliferation protein Ki-67 in adult mice. Although these cells were ...

One striking feature of neuronal transcripts is the abundance of very small exons referred to as microexons, often defined as exons ≤30 nucleotides (nt) in length (Volfovsky et al, 2003). Microexons ...

Telomere shortening occurs in multiple tissues throughout aging. When telomeres become critically short, they trigger DNA-damage responses and p53 stabilization, leading to apoptosis or replicative ...

Abstract Chromatin modifications play an important role in transcription, DNA replication and repair. Nonetheless, whether histone modifications regulate replication stress responses remains obscure.