250+ Clinical Trials: Hosted at Alpha Clinics for CIRM funded and other research. 2000+ Patients Enrolled: Pioneers who participated in a clinical trial at an Alpha Clinic. 40+ Diseases & Conditions: ...

The California Cell and Gene Therapy Manufacturing Network was established by CIRM to expand the manufacturing capabilities necessary to bring stem cell and gene therapies from foundational research ...

CIRM is supporting a network of 11 Shared Resources Laboratories (SRLs) for Stem Cell-Based Modeling, an important component of CIRM’s Infrastructure Program designed to address challenges that hinder ...

CIRM Disclaimer: The information in the table has been collected by CIRM to help CIRM awardees accelerate the development of pluripotent stem cell-derived therapeutics. The information is intended to ...

心肌细胞（CM）是不可再生的。 自我更新的多能人类胚胎干细胞 (hESC) 可以分化为用于细胞疗法的 CM。 在成人CM中，Ca (2+)诱导的Ca (2+)通过兰尼碱受体 (RyR)从肌浆网 (SR)释放是兴奋-收缩耦合的关键。 因此，hESC 衍生的 CM 需要具有适当的 Ca (2+) 处理特性，才能与受体心脏成功进行功能整合。 在这里 ...

心肌细胞（CM）是不可再生的。 自我更新的多能人类胚胎干细胞 (hESC) 可以分化为用于细胞疗法的 CM。 我们最近报道，Ca (2+) 处理对于 hESC 衍生的 CM (hESC-CM) 的兴奋-收缩耦合至关重要，具有功能性但不成熟。 胞质Ca (2+)瞬时幅度较小、动力学较慢和肌浆网 (SR)Ca (2+)含量减少等不成熟特性可归因于特定Ca ...

Research Objective Approximately 20,000 babies are born annually with kidney disease; the long-term outcome is poor. These studies address new ways to develop mini-kidney structures for ...

Fundación – Proyectos de investigación en etapa de descubrimiento Universidad de California en Los Ángeles Superación de barreras para la terapia génica con células madre de las vías respiratorias ...

Projets au stade des essais cliniques Université de Californie, Los Angeles Programme de tolérance immunologique retardée après transplantation rénale de l'UCLA $6,717,608 Recevez les dernières ...

Aux États-Unis, le temps d'attente dépasse cinq ans, la Californie étant particulièrement touchée, avec des délais d'attente moyens bien plus longs que dans d'autres régions du pays. En évitant la ...

Traumatic brain injuries (TBI) are the seventh leading cause of disability globally with 48.99 million prevalent cases and 7.08 million years lived with diability. Approximately 80 % of TBI patients ...

Pursuant to Executive Order N-29-20, certain provisions of the Bagley-Keene Open Meeting Act are suspended due to a State of Emergency in response to the COVID-19 pandemic. Consistent with the ...