Clinical data from the OT‑101 P001 PDAC study suggest that targeting TGFB2 merits additional evaluation in younger patients; ...

Comparison of pH dependencies of the Tetrahymena ribozyme reactions with RNA 2´–substituted and phosphorothioate substrates reveals a rate–limiting conformational step.

The phosphorothioate oligonucleotide fomivirsen is reputed to act by antisense inhibition of human cytomegalovirus (HCMV) immediate early 2 expression.