The San Francisco 49ers will be missing two of their best players in their must-win matchup against the Green Bay Packers ...

While the status of quarterback Brock Purdy has dominated headlines, injuries to tackle Trent Williams and defensive end Nick ...

The San Francisco 49ers will be without their starting quarterback and their best defensive player when they visit the Green ...

Entering an important matchup with the Green Bay Packers on Sunday, the San Francisco 49ers will be without starting ...

Big news and not good news out of the Bay Area on Friday. The 5-5 San Francisco 49ers will be in Green Bay on Sunday to play ...

Brandon Allen will start in place of an injured Brock Purdy when the 49ers (5-5) also have to play without Nick Bosa on ...

San Francisco 49ers quarterback Brock Purdy will miss Sunday's game against the Green Bay Packers with a sore throwing ...

San Francisco 49ers star edge rusher Nick Bosa left Sunday's game with an injury before the Seahawks rallied to win the NFC ...

The 49ers have allowed 222 points, or 22.2 points per game, tied for 16th. Last year, the defense allowed 298 points, or 17.5 ...

The 49ers have ruled out quarterback Brock Purdy for Sunday’s game against the Packers. It appeared to be trending that way ...

The San Francisco 49ers are expecting to get star tight end George Kittle back this week for a key game against Green Bay, ...

Nick Bosa’s injury definitely hurt the 49ers in loss to Seahawks and there’s concern he could miss additional time.