San Francisco 49ers defensive end Nick Bosa missed Wednesday's practice as the team began preparations for Sunday's game ...

Bills' QB Josh Allen is the current favorite for MVP. Expectations aren't something I like to make a habit. However, it's ...

Simpson carried the ball 29 times against the Lions and set a new NFL record with 273 rushing yards, breaking his own record ...

George Kittle will lead the San Francisco 49ers into their matchup versus the Buffalo Bills at Highmark Stadium on Sunday at ...

While the 49ers look like an easy opponent, San Francisco's health could be a major factor in the game, warns one NFL expert.

Josh Allen and the Buffalo Bills are coming off their bye week with a 9-2 record and a four game lead in the division.

The Bills appear to be getting closer to getting a key piece of their defense on the field for the first time this season.

Former Buffalo Bills quarterback Ryan Fitzpatrick recently sang the praises of current field general Josh Allen.

Orchard Park, N.Y. (WHAM) — Bills rookie running back Ray Davis has always searched for a place to call home. "I didn't live ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

Following their bye week, the Bills (9-2) will take on the San Francisco 49ers (5-6) at Highmark Stadium in Week 13. But ...

Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...