The results were ugly for the San Francisco 49ers last week against the Green Bay Packers without starting quarterback Brock ...

SportsLine's model has simulated San Francisco vs. Buffalo on Sunday Night Football 10,000 times and revealed its SNF picks ...

Coming into the 2024 NFL season, it wouldn't have been out of the ordinary to find a Super Bowl prediction featuring the ...

The National Weather Service has extended its "lake effect snow warning" in Buffalo through Monday at 7 p.m. ET, with ...

San Francisco's starting quarterback missed last week's loss to the Packers. Here's the latest on whether he'll play in primetime on Sunday.

The San Francisco 49ers (5-6) try to salvage their season against the Buffalo Bills (9-2) on Sunday Night Football. Kickoff ...

The Buffalo Bills played the Kansas City Chiefs in their last game before heading into the bye week. They pulled off the ...

The Game Matchups Preview series is dedicated to breaking down how the Buffalo Bills match up with their opponent in every ...

San Francisco 49ers head coach Kyle Shanahan spoke with reporters via a conference call on Monday, providing several injury updates following the team's 38-10 loss to the Green Bay Packers. ...

Dive into the San Francisco 49ers vs. Buffalo Bills showdown with a look at odds, predictions, and the best betting options.

It was one of the best plays of the NFL season, and by the time he reached the celebration in the locker room ... another ...

Star pass-catcher George Kittle and the San Francisco 49ers meet the Buffalo Bills on Sunday at 8:20 p.m. ET at Highmark ...