Vitamin B1 (Thiamine) Deficiency Runners on low-calorie diets may be prone to vitamin B1 deficiency. This deficiency can result in symptoms like heavy and tired legs, muscle cramps, and fatigue.

Symptoms of thiamine deficiency can be vague and hard to diagnose. They may include loss of appetite, fatigue (tiredness), irritability, nerve damage, tingling in your arms and legs, blurry vision ...

A deficiency can result in muscle weakness, cramps, and pain, particularly in the legs and feet. In severe cases, it may lead to muscle wasting and difficulty walking. 4.

Vitamin B1 helps your organs and nerves relay messages to one another, such as when your brain tells your leg muscle to twitch. Signs and symptoms of a vitamin B1 deficiency ...

Vitamin B1, or thiamin, is essential for glucose metabolism and healthy nerve, muscle, and heart function. A deficiency of vitamin B1 can be fatal.