Maridebart cafraglutide (known as MariTide) is a long-acting peptide–antibody conjugate that combines glucagon-like peptide-1 receptor agonism and glucose-dependent insulinotropic polypeptide receptor ...

In previous treat-to-target trials, adjustments to the dose of basal insulin have been made at least weekly, according to ...

Semaglutide at a dose of 2.4 mg has established weight-loss and cardiovascular benefits, and cagrilintide at a dose of 2.4 mg ...

One of the more difficult decisions for patients with poorly controlled type 2 diabetes, as well as for their clinicians, is ...

Intracranial aneurysms are common, and the risk of rupture is influenced by size, location, morphology, and factors such as ...

Explore the current issue of The New England Journal of Medicine (Vol. 392 No. 23).

Does immune checkpoint blockade have a role in the treatment of metastatic mismatch repair–deficient (dMMR) tumors? Mismatch repair–deficient tumors are highly sensitive to immune checkpoint ...

Explore this issue of The New England Journal of Medicine (Vol. 0 No. 0).

The current crisis in the United States is bigger than politics, and it deeply affects the health and lives of our patients and communities. Now is the time for physicians to harness their power ...

Preclinical and observational studies suggest that exercise may improve cancer outcomes. However, definitive level 1 evidence is lacking. In this phase 3, randomized trial conducted at 55 centers ...

A 53-year-old woman presented with progressive headache, gait instability, and weight loss. An MRI of the head showed two contrast-enhancing lesions. Tests for antibodies to HIV type 1, HIV type 2 ...

We and others identified retinoblastoma features that suggested that the tumors originate in long- and medium-wavelength cone precursors, and we discovered features of these cone precursors that ...