Vikram Gharge, Anil Gadhe and Vikas Mohite et al. Stability Indicating RP-HPLC Method for the Estimation of Impurities in Esomeprazole Gastro-Resistant Tablets by AQbD Approach. BIOI. 2024. Vol. 5(1).

Improvements in HPLC are sure to continue, but perhaps not from the direction one would assume. New HPLC systems seem to be more focused on regulatory compliance and fitting into a more automated ...

A more efficient alternative to elution Prep-RP-HPLC would be to use it in the displacement mode. Table I, entry 2 describes the displacement Prep-RP-HPLC of a 25 amino acid peptide.Although ...

A rapid peptide mapping method using reverse phase (RP) chromatography, or RP-high performance liquid chromatography (HPLC) with UV detection has been developed for estimating site-specific oxidation ...

Reverse-phase HPLC shows poor retention for hydrophilic analytes, is incompatible with some aqueous mobile phases, and has a limited selectivity range.

RP-HPLC can also be used to study the encapsulation and release of active ingredients in nanoparticles. For example, the RP-HPLC method with 0.1% trifluoroacetic acid as a mobile phase can be used to ...

To accurately assess the background signal in the HPLC-DAD and LC-MS chromatograms, each of the water sources was passed through an RP-C18 column, under conventional flow conditions and without ...

Normal phase HPLC is a valuable technique for the separation of polar and hydrophilic compounds and for isomer separation. Normal phase HPLC requires a polar stationary phase combined with non or ...