IN animals, sulphonamides are detoxified most commonly by acetylation of the free amino-group, a process usually localized in the liver1. In the course of a study of the movement of sulphanilamide ...

NICOTINIC acid has been found to be especially important as a supplement to sulphanilamide therapy of pneumonia. In a series of cases, it has been noted that there frequently occurs in victims of ...

THE key event in the emergence of antibiotics, says Thomas Hager, was not the introduction of penicillin in the 1940s but the discovery of sulphanilamide, a synthetic antimicrobial drug, a decade ...