Fragment-based methods have made substantial contributions to drug discovery in the past 20 years, particularly for challenging targets. Erlanson and colleagues discuss progress in the field, key ...

People sometimes have a hard time believing a forest fragment as small as the ones in Ankafobe still hold much wildlife. Here, an undescribed species of mouse lemur that lives there.

Achieving quality diffracting crystals remains the major bottleneck in macromolecular X-ray crystallography. Antibody fragments have been used to aid structural analysis of complex macromolecules ...

Object Details Collection Freer Study Collection Credit Line Gift of John A. Pope Accession Number FSC-P-3279 Restrictions & Rights Usage conditions apply Type Vessel Related Online Resources Google ...

A new crystallographic screen shows that at room temperature, some small molecule fragments can bind in different poses or to different sites of a target protein altogether.

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Use of small-fragment cortical lag screws maintained reduction in coronal plane fractures associated with supracondylar intercondylar distal femur fractures, according to recently published data ...

Scientists have described a group of small DNA fragments that are key in neuron regulation and maturity. The discovery reveals the importance of these small fragments and their relationship with ...

A new study from Karolinska Institutet shows how a small antibody fragment can block fertilization by targeting a key protein on the surface of the egg.