Underlying GPA should be considered a possible cause of diffuse alveolar hemorrhage, with or without glomerulonephritis. A case report has been published of a patient with granulomatosis with ...
Oral manifestations may be the first signs of granulomatosis with polyangiitis, thus early diagnosis and treatment are key. A patient who initially presented with oral disease was eventually diagnosed ...
The results showed that PB BAL offered deeper alveolar sampling while avoiding contamination from the larger airways. It also revealed incremental changes in the small airways and alveoli, aiding in ...
In addition to reduced RBC transfusion requirements, hemolysis markers significantly improved with the combined therapy. Results from a phase 2 clinical trial evaluating the use of dose-escalated ...
Disease flares were chosen as the basis for the primary endpoint because of their effect on the health and well-being of patients. IgG4-RD disease flares represent periods of inflammation and fibrosis ...
Tertiary lymphoid structures were present in 61.3% of the liver tissues obtained from patients with PBC. Tertiary lymphoid structures are characteristics of lymphocyte accumulation in the portal ...
ADI-001 therapy demonstrated a strong safety profile with low rates of cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome. Researchers have developed a novel T-cell ...
Patients in the PAH group had a higher prevalence of metabolic abnormalities and hyperparathyroidism, and lower bone mineral density than controls. For physicians who treat pulmonary arterial ...
A patient with PLA2R-positive membranous nephropathy later developed IgG4-related autoimmune pancreatitis and renal masses, which resolved with glucocorticoid therapy. Glucocorticoid therapy ...
Most patients had less than 3 relapses, less than 5 days of cumulative hospitalizations, and less than 1 readmission to the hospital in a year. The severity of neuromyelitis optica spectrum disorder ...
KB-208 demonstrated comparable efficacy to intravenous immunoglobulin for treating immune thrombocytopenia in 3 mouse strains, with significantly lower dosing requirements. KB-208, a small molecule ...
Are the out-of-pocket costs of your medications taking a toll on your finances? Rising drug costs are happening to many people with neurological diseases, but people with multiple sclerosis (MS) ...