Maridebart cafraglutide (known as MariTide) is a long-acting peptide–antibody conjugate that combines glucagon-like peptide-1 receptor agonism and glucose-dependent insulinotropic polypeptide receptor ...

In previous treat-to-target trials, adjustments to the dose of basal insulin have been made at least weekly, according to ...

Semaglutide at a dose of 2.4 mg has established weight-loss and cardiovascular benefits, and cagrilintide at a dose of 2.4 mg ...

Intracranial aneurysms are common, and the risk of rupture is influenced by size, location, morphology, and factors such as ...

One of the more difficult decisions for patients with poorly controlled type 2 diabetes, as well as for their clinicians, is ...

Head and neck cancer was the seventh most common cancer worldwide in 2018 (890,000 new cases and 450,000 deaths), 1 accounting for 3% of all cancers (51,540 new cases) and just over 1.5% of all ...

Much progress has been made recently in our understanding of hepatitis B. The authors review virologic and pathogenetic features, diagnosis, established and new treatments, and disease control and ...

Drug-induced liver injury is an uncommon but challenging clinical problem with respect to both diagnosis and management. 1-3 Its incidence is estimated to be 14 to 19 cases per 100,000 persons ...

Hereditary angioedema is a rare, potentially life-threatening disorder characterized by attacks of cutaneous and submucosal swelling. Quincke first described its clinical presentation, and Osler ...

The authors review the epidemiology, pathophysiology, and treatment of alcohol-associated hepatitis, including the evidence for glucocorticoids and liver transplantation.

In a double-blind trial, we randomly assigned participants with type 1 diabetes, a serum urate level of at least 4.5 mg per deciliter, an estimated GFR of 40.0 to 99.9 ml per minute per 1.73 m 2 ...

Explore the current issue of The New England Journal of Medicine (Vol. 392 No. 23).