Monosomal karyotype (MK) refers to the presence of two or more distinct autosomal monosomies or a single monosomy associated with a structural abnormality. In acute myeloid leukemia, MK has been ...

Monosomy X, or Turner syndrome, is a genetic condition affecting people assigned female at birth. Those with it lack part or all of one X chromosome. But this doesn’t mean you can’t lead a ...

Conclusions: A suspect diagnosis of NF1, JMML was confirmed when bone marrow was sent for cytogenetics, that were consistent with monosomy -7 (14 out of 16 metaphases). The patient was transferred to ...

Kevin Shannon, MD, has been studying the genetics of familial monosomy 7 disorder for 30 years. A decades-old medical mystery has been solved by researchers at UC San Francisco and St. Jude Children’s ...

Loss of chromosome 7 was most common, but outcome of AML patients with single monosomy −7 (n = 63; 4-year OS, 13%) and other single autosomal monosomies (n = 46; 4-year OS, 12%) did not differ.