The San Francisco 49ers' visit to Buffalo could be more painful than expected for Kyle Shanahan following the loss to the ...

The 49ers just lost their second game in a row by at least 25 points for the first time since Jim Tomsula was the head coach.

The San Francisco 49ers received some brutal news on Sunday evening. According to head coach Kyle Shanahan, running back ...

Rather than viewing this team as one of the class organizations of the NFC, we now need to ponder whether injuries, age, and ...

San Francisco 49ers running back Christian McCaffrey could be done for the season after just four games. As head coach Kyle ...

Achilles tendinitis robbed San Francisco 49ers star Christian McCaffrey of the first eight games of the 2024 NFL season. A ...

Christian McCaffrey's 2024/25 NFL season could be over in a devastating blow to the San Francisco 49ers after the 28-year-old ...

The 49ers were among the preseason favorites to win the Super Bowl, but now they look like long shots to make the playoffs.

Purdy missed the 49ers' Week 12 contest versus the Green Bay Packers last Sunday with a right shoulder injury—a game San ...

San Francisco head coach Kyle Shanahan discussed what it will take for the 49ers to ignite receiver Deebo Samuel’s production ...

Neil Reynolds, Jeff Reinebold and Phoebe Schecter discuss San Franciscos playoff prospects on the Inside The Huddle Podcast; ...

The Buffalo Bills easily got past the San Francisco 49ers 35-10 on a snowy Sunday Night Football matchup. Here are winners ...