Germ cells are highly specialized cells that form gametes, and they are the only cells within an organism that contribute genes to offspring. Germline stem cells (GSCs) sustain gamete production ...

Producing germ cells in vitro would open important new avenues for regenerative medicine, and obtaining alternative sources of pluripotent stem cells is desirable. In this regard, Geijsen et al ...

Researchers from Japan and France have successfully reconstituted the development of mouse egg cells, known as oocytes, from ...

Patterns in primordial germ cell migration Date: January 7, 2021 Source: University of Münster Summary: Biologists and mathematicians have investigated how primordial germ cells behave in ...

Expanding homogeneous culture of human primordial germ cell-like cells maintaining germline features without serum or feeder layers. Stem Cell Reports, 2022; DOI: 10.1016/j.stemcr.2022.01.012; ...

Primordial germ cells, which emerge around day 16 in early human embryos, develop to form oogonia so that eventually, the number of oocytes that are present in an adult female is fixed at birth.

Primordial germ cell-like cells (PGCLCs), generated in vitro from the stem cells of rats, undergo gametogenesis in vivo and yield normal rat offspring, a new study demonstrates.. While the birth ...

One essential step for a germ cell, one giant leap for the future of reproductive medicine ASHBi researchers now reveal the mechanisms driving epigenetic reprogramming and differentiation during ...

Germ cell tumors constitute a diverse group of rare tumors, which occur in the testes, ovaries and also in other places. Some germ cell tumors exist prenatally, while others present during or ...