综合上述研究结果，研究人员发现 IPMK 在 Th1 和 Th17 细胞极化条件下表达升高，而在 Th2 细胞极化条件下无明显变化。 通过构建 CD4 + T 细胞特异性 IPMK 基因敲除小鼠模型，研究人员发现 IPMK 缺失会导致 Th1 免疫反应减弱，使小鼠对利什曼原虫感染更易感；同时，Th17 细胞功能受损，EAE 疾病严重程度减轻。

结合其他Anogen定量细胞因子ELISA试剂盒，Th1/Th2/Th17细胞因子多重ELISA试剂盒有望用于研究各种疾病模型中细胞因子表达与T辅助 ...

T helper lineages and subsets. CD4 T helper cells can be divided into at least four lineages, namely, Th1, Th2, Th17 and Treg. These cells express master transcription factors (shown inside the ...

此外，注意到 Th17 样 Treg/Th17 细胞失衡，表现为 Th17 样 Tregs 频率降低和 Th17 细胞比例增加。进一步分析揭示 Th2 样 Tregs 的频率与 IL-2RA rs3118470 的风险变异之间存在相关性。值得注意的是，体重正常的 T1D 患者比偏瘦和超重的患者具有更高频率的 Th1 样 Tregs。

These pre-configured multiplexed bead-based kits can be used to quantitate Th1 and Th2 (4-, 6-, or 9-plex) or Th1, Th2, and Th17 (7-plex) associated cytokines in cell supernatants.

“Th1, Th2 and Th17 Inflammatory Pathways Synergistically Predict Cardiometabolic Protein Expression in Serum of COVID-19 Patients.” Molecular Omics 18 (5): 408–16.

A new review was published as the cover paper of Aging, titled "Types of cell death and their relations to host immunological ...

A new review was published as the cover paper of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web ...

VEGFR2 expressions in circulating T cell subsets (Th1, Th2, Th17, CTL) were analyzed by flow cyctometry. Results: Age and gender were not different between the all study groups. Mean circulating CD4+ ...

These findings underscore that Th17 cell durability offers promise for next ... "In contrast to CD8 + or Th1 cells, we discovered Th17 cells could be expanded to large numbers without ...

Reagents That Distinguish Th1 and Th2 cells Courtesy of R&D SystemsSchematic representation of cytokines influencing the development of antigen-activated naive CD4+ T cells into Th1 and Th2 cells.