Polysialic acid (polySia) is mainly attached to NCAM (polySia-NCAM) and has an essential role in regulating NCAM-dependent developmental processes that require plasticity, ...

A group from Nagoya University in Japan has developed a simple, accurate, and sensitive method for measuring polysialic acid, a unique acidic glycan found in the brain. Polysialic acid fluctuates in ...

The body's own polysialic acid may be key in flipping the switch on MS inflammation and nerve damage Depositphotos Multiple sclerosis (MS) is a debilitating inflammatory autoimmune disease that ...

Re-purposing 5-Nonyloxytryptamine and Epirubicin as Polysialic Acid Mimetics for Protection from MPP+-induced Cytotoxicity in Human Neuronal Cells. Article Publication Date. 25-Mar-2025.

"Polysialic acid has been found on the surface of a number of different human cancers. When these cancer cells start to spread, they appear to get more polysialic acid on their surface.

Polysialic acid is a unique acidic glycan that exists mainly in the regions of the brain involved in memory and emotion. However, it is also found in the blood at a certain level, ...

Researchers have designed peptide ligands with the ability to selectively bind to polysialic acid, which may prove useful in the treatment of a variety of diseases, such as Alzheimer’s, Parkinson’s ...

Thermo Fisher Scientific has announced a high-performance anion-exchange with pulsed amperometric detection (HPAE-PAD) method for the analysis of a homologous series of polysialic acids. Application ...

Lipoxen plc (AIM: LPX), a bio-pharmaceutical company specialising in the development of differentiated biologicals, vaccines and siRNA delivery, said it has ...