The investigational oral pre-exposure prophylaxis (PrEP) agent MK-8527 showed a similar, well-tolerated safety profile to ...

Low-dose melatonin improved drug absorption but did not reduce delirium in individuals with critical illness and who were ...

Drug efficacy and safety are tied to a clear understanding of how the body processes medications.

Cite this: Pharmacokinetics and Pharmacodynamics of Intranasal Versus Intravenous Fentanyl in Patients with Pain after Oral Surgery - Medscape - Oct 01, 2008.

Drug Metabolism and Pharmacokinetics The NMR and Drug Metabolism Core has developed rapid and efficient approaches to investigate metabolism, metabolic stability, pharmacokinetics (PK), and chemical ...

Haloperidol is an antipsychotic medication that is available as an oral preparation as well as intravenous and intramuscular injections.

Pharmacokinetics, or the movement of drugs in the body, affects the probability of addiction to that drug. Fast entry of the drug into the brain tends to make the drug more addictive.

Purpose. A pooled analysis of six clinical studies was conducted to describe the pharmacokinetics of extended-release epidural morphine sulfate. Methods. Data from six clinical studies evaluating ...

ADME is the abbreviation for Absorption, Distribution, Metabolism and Excretion. ADME studies are designed to investigate how a chemical (e.g., a drug compound) is processed by a living organism.

Early-phase data support dose-optimized subcutaneous blinatumomab as a promising approach for relapsed or refractory B-cell ...

Pharmacokinetics: The pharmacokinetic profile of DF-003 was largely dose proportional and the data support additional clinical trials as a once-daily, orally administered drug.