研究发现，棒曲霉素（Patulin），以及在较小程度上的异戊烯基醌（Xestoquinol），在体外、酵母细胞和人类细胞中均能抑制 TOP1 的第一步催化反应。 特别是棒曲霉素（Patulin）能够阻止由拓扑异构酶 1 “毒药” 喜树碱（CPT）引起的 TOP1 裂解复合物在人类细胞中的积累。

Patulin (C 7 H 6 O 4), a mycotoxin produced by several types of fungi, is toxic to a variety of life forms, including humans, mammals, plants, and microorganisms.In particular, environments ...

IN November, 1943, a group of British investigators reported on a new antibiotic agent, patulin, obtained from a strain of Penicillium patulin.1 This substance was considerably more toxic than peni ...

S. Martinelli & Co is recalling nearly 174,000 bottles of apple juice sold in 28 states. The recall is over potential contamination with patulin, a toxin produced by mold, according to a notice ...

Any patulin already present in apples is not destroyed by pasteurization. Survey results Almost 300 products were purchased from all states and territories in 2021 and 2022.

Slicing away at contamination risk in fruit, Scottish scientists overcome obstacles to design a rapid test for the detection of the harmful mycotoxin patulin that occurs in naturally occurring moulds.

Creative Diagnostics Patulin Test Reagents provide food manufacturers with a reliable and accurate method for detecting Patulin in apple juice, applesauce, baby food and other apple products. By ...

Several countries have instituted patulin restrictions in apple products. Additionally, the World Health Organization recommends a maximum concentration of 50 micrograms/liter in apple juice.

Patulin can cause cause nausea, gastrointestinal disturbances and vomiting; Only bottles of Pick'd Apple Juice with certain use by dates are affected ...

For those of you unfamiliar with the connection between apple juice and the toxin, patulin, a new study adds weight to a growing body of research suggesting there are unhealthy levels of patulin in ...