Oncogene - HOXA1-stimulated oncogenicity is mediated by selective upregulation of components of the p44/42 MAP kinase pathway in human mammary carcinoma cells. Skip to main content.

来自纪念斯隆·凯特琳癌症中心、威尔·康奈尔医学院、西奈山医学院、Genentech、礼来公司、哥伦比亚大学、Sema4和ORIC Pharmaceuticals的研究团队，最近在《科学》杂志上发表了一篇重要研究论文- Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors。

Oncogene - p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment Skip to main content Thank you for visiting ...

As Dr. Hsieh stated, this work was a true “tour de force” by Dr. Samantha Schuster, a recent PhD graduate from the Hsieh Lab that uncovered how mutations present in the 3’UTR of advanced prostate ...

Mutant RAS Proteins Team Up for Oncogenicity. Mice with cancer whose KRAS proteins couldn’t link together had much better survival outcomes than those whose oncogenic mutant paired with wild-type KRAS ...