Nonselective β-blockers are often used in patients with cirrhosis and esophageal varices to prevent variceal bleeding. A recent study has suggested that nonselective β-blockers promote more harm ...

Carvedilol is a nonselective β-blocker that has weak vasodilating properties owing to alpha-1 blockade, and has never been tested for the primary prophylaxis of variceal bleeding.

New data published in Hepatology showed that nonselective beta-blockers did not increase all-cause or cirrhosis-related mortality in patients with advanced cirrhosis and ascites.“In 2010 ...

Venkatrao Medarametla 1, Stephen Festin 2, Chuluunbaatar Sugarragchaa 2, Alexander Eng 2, Amir Naqwi 3, Timothy Wiedmann 4, Lawrence S. Zisman 1,25, PK10453, a nonselective platelet-derived growth ...

Naproxen, the nonselective NSAID used in the VIGOR trial, may be protective against cardiovascular events. 22 Naproxen has an extended half-life and may have completely suppressed the capacity of ...

Citation: Chan CC, Reid CM, Aw TJ, Liew D, Haas SJ, Krum H. Do COX-2 inhibitors raise blood pressure more than nonselective NSAIDs and placebo? An updated meta-analysis. Hypertension. 2009;27:2332 ...

Once we had that result, we predicted that people who happened to be on a nonselective beta blocker that would inhibit beta-2 and beta-3, but not a beta-1 selective inhibitor, would show delayed ...

"It is probably acceptably safe to take many of the NSAIDs," said researchers based on their trial of patients at low cardiovascular risk, whose follow-up was cut short after funding was pulled.

Nonselective beta-blockers (eg, propranolol, nadolol, timolol, and pindolol) act on both β1- and β2-adrenergic receptors, whereas selective beta-blockers target mainly β1-adrenergic receptor.

NSAIDs, which can be selective or nonselective, are effective for pain relief, easily accessible, and inexpensive. Plus, they can be a safer alternative to opioids for individuals with chronic pain.