本研究系统地阐明了外源补充NADPH通过直接与NMT2结合上调FSP1 N-肉豆蔻酸化，从而触发铁死亡防御信号的分子机制。这为NADPH用于治疗涉及铁死亡的 ...

为探究线粒体烟酰胺腺嘌呤二核苷酸磷酸（nadph）的具体功能，研究人员开展相关研究。结果发现 nad+激酶 2（nadk2）对维持蛋白质脂酰化、线粒体脂肪酸合成（mtfas）活动至关重要，其缺乏会影响线粒体功能。该研究揭示了线粒体 nadph 的关键作用。

nadph在分裂期的动态变化只发生在非整倍体肿瘤细胞中，近二倍体的肿瘤细胞并没有这个现象。 接着，通过筛选寻找到了促进分裂期NADPH上调的关键 ...

NADPH（还原型辅酶Ⅱ）是细胞内关键的抗氧化分子，它参与生物体内还原性生物合成以及氧化还原反应，在代谢通路中发挥重要作用。但细胞如何 ...

为探究亮丙瑞林（Leuprorelin）在大鼠体内外的代谢情况以及 NADPH 对其代谢的影响，研究人员通过体外和体内实验展开研究。结果发现大鼠肝、肾 S9 组分与人类一样存在 NADPH 依赖的代谢现象，且肾 S9 组分在无 NADPH 时与体内相关性最佳。该研究为肽类药物研发提供了重要参考。

中国药科大学药学院丁娅团队在Angew Chem发表NADPH响应的核壳结构酶-前药反应器最新研究成果 PPS . 近日，国际著名期刊Angewandte Chemie International Edition ...

We also examined superoxide production in neurons prepared from Ncf1 −/− (also known as p47 phox) mice to confirm the role of NADPH oxidase in NMDA-induced superoxide production.Cells from p47 ...

Yuanfang Guo, Jie Wang, Dongmei Zhang, Yufeng Tang, Quanli Cheng, Jiahao Li, Ting Gao, Xiaohui Zhang, Guangping Lu, Mingrui Liu, Xun Guan, Xinyu Tang, Junlian Gu, Diabetes-associated sleep ...

NAD+, NADH as well as NADP+, NADPH have been known to play vital roles in energy metabolism, antioxidation, and reductive biosynthesis. Changes in these systems can be monitored using absorbance ...

Biosensors show the ratio of NADPH to NADP⁺ in real time / Insights into the evolution of the protective function of cells Biological cells have many vital functions in the organism. For example, they ...