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这项研究揭示了激活的系膜细胞与cx3cr1 + 单核/巨噬细胞相互作用促进mspgn肾小球区域免疫损伤的机制,为cx3cl1-cx3cr1轴作为mspgn治疗新靶点提供了证据。 相关成果发表在《Research》杂志上。
Objective: To further clarify whether the antisense MCP-1 have renal protective role in MsPGN rats. Method: Rats were induced mesangial proliferative glomerulonephritis by injected Thy-1 antibody ...