Methacholine challenges were performed, with doses from 0.15 to 200 μmol, using a modification of the method of Chai et al. 21, 22 Lung function was measured after each dose, by Rrs and Xrs ...

Methacholine had less troublesome side effects than histamine, but hypotension, salivation, nasal congestion, flushing, tachycardia and sweating were commonly noted.

Background Methacholine hyperresponsiveness is prevalent in elite athletes. Comparative studies have hitherto been limited to methacholine, eucapnic voluntary hyperpnoea and exercise. This study ...

Allergen and methacholine immediately induced similar levels of bronchoconstriction. Eosinophilic inflammation of the airways increased only in the allergen group, whereas both the allergen and ...

The guidelines [1] on using methacholine challenge testing (MCCT) to evaluate for airway hyperresponsiveness (AHR), published in 2000, provided a figure that allowed clinicians to calculate ...

When methacholine binds M3, the mast cells release serotonin. This then acts on nerve cells, which in turn control the airways. Thereafter, the airways produce acetylcholine, ...

When methacholine binds M3, the mast cells release serotonin. This then acts on nerve cells, which in turn control the airways. Thereafter, the airways produce acetylcholine, ...

WEST COLUMBIA, S.C., July 6, 2020 /PRNewswire/ -- Nephron Pharmaceuticals Corporation, one of the fastest-growing pharmaceuticals companies in the country, today announced a new collaboration with ...

Peripheral airway response to methacholine was similar among obese adults with and without asthma, although forced expiratory volume was lower for those with asthma, based on data from 53 ...