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经皮给药新突破:离子及纳米结构地氯雷他定 ...
为研究两种含离子及纳米结构(基于吐温 - 80 的胶束形式)地氯雷他定(Desloratadine)的基质贴剂经皮扩散动力学,研究人员利用 Franz 扩散池评估其经纤维素膜和大鼠皮肤的转运效率,并用 UV 光谱法定量测定。结果显示胶束形式的贴剂释药更完全持久,为该药物经皮给药提供新方向。
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