The treatment landscape for primary biliary cholangitis (PBC) has undergone a marked transformation over the past year, driven by the recent approvals ...

O nce clinical suspicion has been established for primary biliary cholangitis (PBC), the " serologic hallmark " of the ...

Primary sclerosing cholangitis is an idiopathic, heterogeneous, cholestatic liver disease that is characterized by persistent, progressive, biliary inflammation and fibrosis. There is no effective ...

Cholangitis is inflammation in your bile ducts that, without treatment, can lead to serious health issues. Cholangitis is a type of liver disease that causes inflammation (swelling) in the bile ...

However, research on quality-of-life outcomes in patients with PBC suggests that effectively managing the condition requires ...

Primary biliary cholangitis is a rare autoimmune disease that slowly damages the liver's bile ducts. Over time, this can lead to liver damage, which can progress to cirrhosis of the liver.

Seladelpar is a drug candidate for the treatment of primary biliary cholangitis that selectively activates PPARδ. 12 PPARδ is unique among PPAR isotypes, with broad expression in cells that play ...

Cholangitis and cholecystitis are two separate conditions that affect the biliary system. While both can be related to gallstones, they each have different underlying causes, symptoms, and treatments.

In some severe cases, acute cholangitis is characterized by hypotension and confusion. Although Charcot’s triad is highly specific (95.9%) for acute cholangitis, it has very low sensitivity (26.4%).

Journalist Annie Lowrey suffers from primary biliary cholangitis (PBC), a degenerative liver disease in which the body mistakenly attacks cells lining the bile ducts, causing them to inflame.

Cholangitis describes inflammation in the bile ducts or biliary system. Some forms of cholangitis can be life threatening. Treatment may involve antibiotics, drainage of the bile duct, and ...

Primary biliary cholangitis is a disease that damages the bile ducts in your liver. Your doctor may also call it PBC. It used to be called primary biliary cirrhosis. These ducts have an important ...