We polled dermatologists for their best serums for mature skin, and then put the formulas to the test. Our top picks suit a range from skin types and budgets, from brands like Olay, SkinCeuticals, and Estee Lauder.

Both Dr. Lolis and Mamina Turegano, MD, a dermatologist, internist, and dermatopathologist in Metairie, Louisiana, are big fans of this cult-classic serum because it contains a powerful and patented blend of vitamins C, E, and ferulic acid, which works hard to correct discoloration and target the signs of aging, like fine lines and wrinkles.

Serums for mature skin often contain ingredients that can be irritating if you introduce them too quickly, like retinol and alpha hydroxyl acids (or AHAs), Dr. Sawaya says. If you

Spread the love NanoTech Renewal Serum Nanoparticle delivery system Targets deep wrinkles Clinically proven results in 2 weeks BioMimetic Youth Elixir Mimics skin’s natural repair process Contains synthetic growth factors Improves skin elasticity and firmness Quantum C+ Brightening Serum Stabilized Vitamin C derivative Enhanced by quantum dot technology Reduces hyperpigmentation and brightens skin Stem Cell Activator Complex Activates skin’s own stem cells Promotes collagen production Improves overall skin texture AI-Formulated Personalized Serum Custom-made based on DNA analysis Adapts to skin’s changing needs Addresses multiple aging concerns simultaneously Epigenetic Youth Booster Targets age-related DNA methylation Reverses cellular aging signs Improves skin’s