Both teams face questions. The Packers will be missing two key defensive players due to injury — cornerback Jaire Alexander and linebacker Edgerrin Cooper. But the 49ers are hurting, too. Quarterback Brock Purdy and defensive end Nick Bosa are out. Backup Brandon Allen will replace Purdy.

The San Francisco 49ers are set to take on the Green Bay Packers on Sunday afternoon, looking for a spark in a big way as they sit at 5-5 on the season. The 49ers are coming off a 20-17 loss to the Seattle Seahawks where they struggled to capitalize on opportunities offensively and had a late meltdown defensively,